The series follows Amanda Vaughn (Leslie Bibb), former high-school "Queen Bitch," a recently widowed mother of two, who returns to her hometown of Highland Park, Texas, an enclave of Dallas. Formerly rich, Amanda Lost everything when her husband was exposed as stealing billions of dollars from investors and died in a car crash with his mistress. She meets the former schoolmates she used to mock: Carlene Cockburn (Kristin Chenoweth), the new "Queen Bitch"; Sharon Peacham (Jennifer Aspen), who was beautiful in high school and is now heavy and insecure and does the bulk of Carlene's bidding; glamorous business mogul Cricket Caruth-Reilly (Miriam Shor), whose husband, Blake (Mark Deklin), is gay; and Heather Cruz (Marisol Nichols), a powerful Dallas real-estate agent. Amanda and her teenage children move in with her 60-something mother Gigi Stopper (Annie Potts), who tries to influence Amanda's parenting and style choices, and gives her advice about strategic maneuvering among these women. While Amanda has grown considerably since high school and wants to move on with her life, Carlene and the others still resent Amanda. They don't believe she's changed and are out to drive her away.